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Published on: January 19, 2024
[PREVALENCE OF IRON DEFICIENCY AND IRON DEFICIENCY ANEMIA IN INFANTS AGED 9 TO 15 MONTHS IN A LOW INCOME POPULATION
Lutfi Jaber1,2,3,4, Shadi Jbarah1,3
1The Bridge to Peace Community Pediatric Center, Taibe.
Insights
Iron deficiency anemia (IDA) affects 4% of Israeli Arab infants, with breastfeeding and iron supplements reducing risk. Further research is needed to establish diagnostic criteria and identify causes of anemia unrelated to iron deficiency.
Area of Science:
- Pediatric Nutrition
- Hematology
- Public Health
Background:
- Iron deficiency (ID) is a widespread nutritional deficiency impacting global health.
- Infant iron status is critical for development and requires monitoring.
Purpose of the Study:
- To determine the prevalence and causes of iron deficiency (ID) and iron deficiency anemia (IDA) in Israeli Arab infants.
- To assess the iron status of infants aged 9-15 months within this population.
Main Methods:
- A cross-sectional study analyzed iron status indicators (hemoglobin, ferritin, MCV) in 410 infants.
- Prevalence of IDA was calculated using established diagnostic criteria.
Main Results:
- Anemia (Hb <11 g/dL) was observed in 28% of infants, while 7% showed low ferritin levels (<12 μg/L).
- Iron deficiency anemia (IDA) was diagnosed in 4% of infants based on specific criteria.
- Prolonged breastfeeding (>6 months) and iron supplementation (>6 months) were significantly associated with a lower risk of anemia.
Conclusions:
- Further research is essential to refine diagnostic cutoffs for ID and IDA and to investigate the causes of anemia not linked to iron deficiency.
- Recommendations include promoting breastfeeding and iron supplementation, with consideration for routine ferritin testing at one year of age.
Background:
Iron deficiency (ID) is a common nutritional deficiency.
Objectives:
To estimate the prevalence and causes of ID and iron deficiency anemia (IDA) and to report the iron status in Israeli Arab infants.
Methods:
Data on iron status was taken from 410 infants, aged 9 to 15 months, who were randomly selected from 2400 infants born between 2005-2010. Hemoglobin (Hb) <11 g/dL, ferritin <12 μg/L and mean corpuscular volume (MCV) <70 fL were the criteria for establishing IDA, and ferritin<12 μg/L and MCV <70 fL for establishing ID.
Results:
Of the 410 infants, 116 (28%) had Hb <11 g/dL, and 68 (17%) had MCV<70 fL. We were able to analyze the samples of 368 infants for ferritin: 27 (7%) had ferritin <12 μg/L. Iron deficiency anemia (Hb <11 g/dL and ferritin <12 μg/L) was diagnosed in 15/368 infants (4%).The IDA rate was 2% (10/368 infants) when the criteria of three factors (Hb <11 g/dL and ferritin <12 μg/L, MCV <70 fL) were used. Infants who were breastfed >6 months were significantly less prone to have anemia (P > 0.002) and infants who received >6 months of iron supplements were also less prone to have anemia (P < 0.05).
Conclusions:
Studies are needed for establishing valid cutoff points for diagnosing ID and IDA and for identifying the causes of the high rate of anemia in the absence of ID. Breastfeeding and iron preparation supplementation are recommended and the test of ferritin at one year of age could be considered.
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