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Obesogens in the aquatic environment: an evolutionary and toxicological perspective
Ana Capitão1, Angeliki Lyssimachou2, Luís Filipe Costa Castro1
1CIMAR/CIIMAR- Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal; FCUP - Department of Biology, Faculty of Sciences, University of Porto, Rua do Campo Alegre, 4169-007 Porto, Portugal..
Environmental chemicals called obesogens disrupt lipid homeostasis in aquatic animals, impacting ecosystems. This review explores their effects across diverse species, linking environmental exposure to the global obesity epidemic.
Area of Science:
- Environmental Science
- Toxicology
- Ecology
Background:
- Obesity is a global health crisis linked to lifestyle and environmental factors.
- Obesogens are chemicals interfering with lipid homeostasis, found in everyday products.
- These obesogens contaminate aquatic environments, posing risks to wildlife.
Purpose of the Study:
- To review the impact of obesogens on aquatic organisms.
- To compare lipid homeostasis pathways across metazoans.
- To understand the link between environmental chemicals and obesity.
Main Methods:
- Literature review of studies on obesogens and aquatic life.
- Comparative analysis of lipid metabolism pathways in different animal phyla.
- Synthesis of evidence linking environmental chemical exposure to obesity.
Main Results:
- Obesogens affect lipid homeostasis in various aquatic taxa.
- Observed effects include altered weight, lipid profiles, and signaling pathways.
- Lipid homeostasis pathways are conserved across ancient animal lineages.
Conclusions:
- Obesogen exposure is a significant factor in aquatic ecosystem health.
- Understanding obesogen effects in aquatic animals can inform human obesity research.
- Further research is needed to identify knowledge gaps and prioritize future studies.
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