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Updated: Feb 27, 2026

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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From in vitro to in vivo: Integration of the virtual cell based assay with physiologically based kinetic modelling

Alicia Paini1, Jose Vicente Sala Benito1, Jos Bessems1

  • 1Chemical Safety and Alternative Methods Unit, EURL ECVAM, Directorate F - Health, Consumers and Reference Materials, Joint Research Centre, European Commission, Ispra, Italy.

Toxicology in Vitro : an International Journal Published in Association with BIBRA
|July 1, 2017
PubMed

Keywords:
DNA adductEstragoleKNIME workflowPBDPBKRisk assessmentVCBA

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