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Published on: July 29, 2014
The Effect of Multimodal Analgesia on Intraoperative Morphine Requirement in Lumbar Spine Surgeries
Keelara Shivalingaiah Savitha1, Radhika Dhanpal1, Apoorwa N Kothari1
1Department of Anaesthesia, St. John's Medical College Hospital, Bengaluru, Karnataka, India.
Background:
Lumbar spine surgery demands intense analgesia. Preemptive multimodal analgesia (MMA) is a novel approach to attenuate the stress response to surgical stimulus.
Aims:
The aim of the study was to assess the intraoperative morphine consumption in patients undergoing lumbar spine surgery.
Patients And Methods:
A randomized, prospective, double-blind study involving 42 patients belonging to the American Society of Anesthesiologists Class I and II scheduled to undergo elective lumbar spine surgery were allocated into two groups of 21 each. Group A (study group) received injection diclofenac sodium, paracetamol, clonidine, and skin infiltration with bupivacaine adrenaline and Group B (control group) received paracetamol and skin infiltration with saline adrenaline. Preemptive analgesia was practiced in both the groups. Intraoperative morphine consumption was documented.
Statistical Methods:
Intraoperative morphine consumption between the two groups was compared using Mann-Whitney U-test. Postextubation sedation score between the two groups was compared using Chi-square test and presented as number and percentage. P < 5% was considered statistically significant.
Results:
Intraoperative morphine consumption was significantly low in the study group (P < 0.001). Postextubation sedation score was comparable between the two groups.
Conclusion:
Preemptive MMA has demonstrated significant morphine sparing effect intraoperatively in patients undergoing lumbar spine surgeries.
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