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Related Experiment Video

Updated: Feb 27, 2026

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes
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Assessment of eye length changes in accommodation using dynamic extended-depth OCT.

Yu-Cherng Chang1,2, Keke Liu1,2, Carolina de Freitas1

  • 1Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

Biomedical Optics Express
|July 1, 2017
PubMed
Summary

This study found that while lens thickness changes with disaccommodation, axial eye length does not significantly change during accommodation. These findings contribute to understanding myopia development and eye growth dynamics.

Keywords:
(170.4500) Optical coherence tomography(330.5370) Physiological optics(330.7322) Visual optics, accommodation(330.7327) Visual optics, ophthalmic instrumentation

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Area of Science:

  • Ophthalmology
  • Optometry
  • Biomedical Optics

Background:

  • Accommodation's role in myopia development is debated.
  • Potential link between axial eye length changes and myopia progression.

Purpose of the Study:

  • To dynamically assess changes in lens thickness and axial eye length during accommodation.
  • Investigate the relationship between accommodation stimuli and ocular biometry.

Main Methods:

  • Utilized an extended-depth optical coherence tomography (OCT) system for dynamic whole eye biometry.
  • Measured changes in lens thickness (LT) and axial eye length (AEL) in young subjects.
  • Applied step disaccommodation stimuli of 2D, 4D, and 6D amplitudes.

Main Results:

  • A significant, stimulus-correlated decrease in lens thickness was observed with disaccommodation.
  • No statistically significant changes in axial eye length were detected during accommodation.
  • Individual variations in the degree of change were noted in previous literature.

Conclusions:

  • Accommodation does not appear to induce significant changes in axial eye length in young subjects.
  • Lens thickness dynamically changes with accommodation, but axial elongation is not a direct consequence.
  • Findings challenge the hypothesis that accommodation-induced axial elongation is a primary driver of myopia.