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Related Experiment Video

Updated: Feb 27, 2026

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[Psoriatic arthritis : Current therapeutic standards].

M Köhm1,2, F Behrens3,4

  • 1Abteilung Rheumatologie, Goethe-Universität Frankfurt/Main, Theodor-Stern-Kai 7, 60596, Frankfurt, Deutschland. Michaela.Koehm@kgu.de.

Zeitschrift Fur Rheumatologie
|July 1, 2017
PubMed
Summary

Psoriatic arthritis (PsA) is a complex immune disease affecting joints and skin. Achieving minimal disease activity is key, with new targeted therapies offering improved patient outcomes.

Keywords:
Minimal disease activityRecommendationsRemissionTherapyTreat-to-target

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Area of Science:

  • Rheumatology
  • Immunology
  • Dermatology

Background:

  • Psoriatic arthritis (PsA) is a heterogeneous immune-mediated disease affecting skin, joints, entheses, and spine, often with comorbidities.
  • Effective, patient-centered therapy selection depends on disease manifestations and influencing factors.
  • Current international treatment guidelines include EULAR and GRAPPA, updated in 2016, but German recommendations are absent.

Purpose of the Study:

  • To address the lack of German treatment recommendations for psoriatic arthritis.
  • To emphasize the treat-to-target strategy, aiming for minimal disease activity when remission is not achievable.
  • To highlight the potential of new molecularly targeted therapies for differentiated PsA treatment.

Main Methods:

  • Review and synthesis of existing international treatment recommendations (EULAR, GRAPPA).
  • Adaptation of the treat-to-target strategy from rheumatoid arthritis treatment.
  • Consideration of emerging targeted therapies for psoriatic arthritis.

Main Results:

  • International guidelines (EULAR, GRAPPA) provide frameworks for PsA management.
  • Minimal disease activity is a crucial therapeutic target in PsA treatment.
  • Novel targeted therapies enable more personalized and effective treatment approaches.

Conclusions:

  • German treatment recommendations for PsA are needed.
  • A treat-to-target strategy focusing on minimal disease activity is recommended.
  • Advancements in targeted therapies offer improved treatment options for PsA patients.