Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

1.6K
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
1.6K
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

1.6K
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Use of Dexmedetomidine With Dexamethasone for Extended Pain Relief in Adductor Canal/Popliteal Nerve Block During Achilles Tendon Repair.

Cureus·2021
Same author

A comprehensive review of the treatment and management of Charcot spine.

Therapeutic advances in musculoskeletal disease·2021
Same author

Declining Utilization and Inflation-Adjusted Expenditures for Epidural Procedures in Chronic Spinal Pain in the Medicare Population.

Pain physician·2021
Same author

Declining Utilization Patterns of Percutaneous Adhesiolysis Procedures in the Fee-For-Service (FFS) Medicare Population.

Pain physician·2021
Same author

Is Epidural Injection of Sodium Chloride Solution a True Placebo or an Active Control Agent? A Systematic Review and Meta-Analysis.

Pain physician·2021
Same author

Treatment and Management of Twelfth Rib Syndrome: A Best Practices Comprehensive Review.

Pain physician·2021
Same journal

Analysis of the Effectiveness of Injection-Based Minimally Invasive Treatment for Piriformis Syndrome: Clinical Outcomes and Anatomical Correlates.

Current pain and headache reports·2026
Same journal

A Systematic Review and Meta-Analysis of Randomized Controlled Trials of Epidural Regenerative Medicine Therapies in Managing Spinal Pain.

Current pain and headache reports·2026
Same journal

Artificial Intelligence in Neuropathic Pain: From Mechanisms to Neuromodulation and Regenerative Strategies.

Current pain and headache reports·2026
Same journal

Proposed Conditions for Pain Reprocessing Therapy Readiness: Beyond Phenotyping Neuroplastic Pain.

Current pain and headache reports·2026
Same journal

Treatment of Headache in Children and Adolescents with POTS.

Current pain and headache reports·2026
Same journal

Pediatric Headache in the Age of Social Media: A Topical Review.

Current pain and headache reports·2026
See all related articles

Related Experiment Video

Updated: Feb 27, 2026

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
05:39

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

Published on: May 26, 2023

2.5K

Paravertebral Blocks for Same-Day Breast Surgery.

Mark R Jones1, Graham R Hadley2, Alan D Kaye3

  • 1Department of Anesthesiology, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA.

Current Pain and Headache Reports
|July 1, 2017
PubMed
Summary
This summary is machine-generated.

Paravertebral block (PVB) offers superior pain relief and reduced opioid use for breast surgery patients compared to traditional methods. Continuous PVB is particularly beneficial for major procedures, potentially improving oncological outcomes.

Keywords:
AnesthesiaBreast surgeryCancer recurrenceOutcomesParavertebral blockTechnique

More Related Videos

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
03:07

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial

Published on: August 19, 2025

1.2K
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

4.5K

Related Experiment Videos

Last Updated: Feb 27, 2026

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
05:39

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

Published on: May 26, 2023

2.5K
Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
03:07

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial

Published on: August 19, 2025

1.2K
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

4.5K

Area of Science:

  • Anesthesiology
  • Surgical Pain Management
  • Oncology

Background:

  • Breast surgery is a common procedure with over 500,000 annual cases in the USA.
  • General anesthesia (GA) has been the standard, with epidural anesthesia considered too invasive.
  • Paravertebral block (PVB) has emerged as a viable alternative for breast surgery analgesia and anesthesia.

Purpose of the Study:

  • To review the evidence supporting paravertebral block (PVB) as an anesthetic or analgesic technique for breast surgery.
  • To compare the efficacy and safety of PVB with traditional anesthesia methods.
  • To evaluate the benefits of PVB for both major and minor breast surgical procedures.

Main Methods:

  • Review of existing literature on paravertebral block (PVB) for breast surgery.
  • Analysis of studies comparing PVB with general anesthesia and systemic analgesia.
  • Evaluation of data on immediate and long-term pain control, opioid consumption, and adverse effects.

Main Results:

  • PVB provides superior immediate and long-term analgesia compared to systemic analgesia.
  • PVB decreases opioid use and associated side effects like nausea and vomiting.
  • Potential benefits include improved oncological survival after mastectomy for malignancy.
  • Continuous PVB is strongly supported for major breast surgery, offering effective pain control and chronic pain reduction.

Conclusions:

  • Paravertebral block (PVB) offers significant perioperative benefits for breast surgery patients.
  • Continuous PVB is highly effective for major breast surgery, managing acute and chronic pain.
  • For minor breast surgery, multimodal analgesia is often sufficient, with PVB as a rescue option or for high-risk patients.