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Updated: Feb 27, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[The frequency of cerebrovascular disorders in patients with different forms of atrial fibrillation]
A V Melekhov1, G E Gendlin1, E M Alekseeva1
1Pirogov Russian National Research Medical University, Moscow, Russia.
Insights
Persistent atrial fibrillation (AF) increases the risk of blood circulation disorders (BCD). Patients with persistent AF received insufficient anticoagulant treatment, highlighting a need for improved BCD prevention strategies.
Area of Science:
- Cardiology
- Internal Medicine
- Vascular Medicine
Background:
- Atrial fibrillation (AF) is a common arrhythmia associated with significant morbidity.
- Blood circulation disorders (BCD) are a major complication in AF patients.
- Understanding BCD frequency across different AF types is crucial for risk stratification.
Purpose of the Study:
- To determine the incidence of BCD in patients with various forms of non-valvular AF.
- To investigate the relationship between AF duration, anticoagulant use, and BCD.
- To assess the adequacy of BCD prevention in different AF subtypes.
Main Methods:
- Retrospective analysis of 1626 non-valvular AF patients' medical records.
- Data collected from Moscow between 2009 and 2015.
- Comparison of BCD frequency and anticoagulant usage across AF classifications.
Main Results:
- Persistent AF patients were older and had higher risks of thromboembolic and hemorrhagic complications.
- BCD incidence was lower in paroxysmal and persistent AF groups compared to persistent AF.
- Anticoagulant use was significantly lower in outpatients (10.8%) vs. inpatients (42.8%), and less frequent in persistent AF.
Conclusions:
- Persistent AF is linked to an elevated risk of BCD.
- Current BCD prevention in persistent AF patients is inadequate compared to less persistent forms.
- Optimizing anticoagulant therapy is essential for reducing BCD in AF patients.
Aim:
To study the frequency of blood circulation disorders (BCD) in patients with different forms of atrial fibrillation (AF) and its relationship with AF duration and treatment with anticoagulants.
Material And Methods:
Medical records and medical history of 1626 patients with non-valvural AF were analyzed in Moscow from 2009 to 2015.
Results:
Patients with persistent AF were older and had a higher risk of thromboembolic and hemorrhagic complications. In the group of patients with paroxysmal and persistent AF, percentage of patients with BCD (including recurrent ones) was decreased by 13.1 and 28.9% compared to the patients with persistent form. There was no correlation between AF duration and BCD frequency. The frequency of using anticoagulants was 10.8% in outpatients and 42.8% in inpatients. Patients with persistent AF received anticoagulants less frequently than patients with less persistent forms.
Conclusion:
Persistent AF is associated with the higher risk of BCD. The prevention of BCD in patients with persistent AF was insufficient compared to that in patients with less persistent forms.
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