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Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Impact of a cardiac intensivist on mortality in patients with cardiogenic shock
Soo Jin Na1, Taek Kyu Park2, Ga Yeon Lee2
1Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Insights
High-intensity staffing in cardiac care units (CCUs) by a dedicated cardiac intensivist significantly reduced cardiogenic shock (CS) mortality. This model improved outcomes for critically ill patients requiring intensive support.
Area of Science:
- Cardiology
- Intensive Care Medicine
- Critical Care
Background:
- Cardiogenic shock (CS) presents a significant challenge in cardiac care.
- Evaluating staffing models is crucial for improving outcomes in critically ill patients.
Purpose of the Study:
- To assess the impact of high-intensity staffing by a cardiac intensivist on clinical outcomes in CS patients.
- To compare mortality rates between low-intensity and high-intensity cardiac care unit (CCU) models.
Main Methods:
- A cohort of 2923 CCU patients was analyzed.
- A transition from low-intensity to high-intensity staffing occurred in January 2013.
- Eligible patients (n=513) with CS requiring vasopressors/inotropes and elevated lactate were compared between the two staffing models.
Main Results:
- High-intensity CCU staffing was associated with a significant reduction in CCU mortality (17.6% vs 30.6%, aOR 0.44).
- No significant difference in in-hospital mortality was observed between groups (24.4% vs 33.1%).
- In patients treated with extracorporeal membrane oxygenation (ECMO), high-intensity staffing significantly lowered both CCU and in-hospital mortality.
Conclusions:
- High-intensity CCU staffing by a dedicated cardiac intensivist is linked to improved survival in CS.
- This staffing model demonstrates particular benefit for CS patients requiring advanced life support like ECMO.
Background:
This study aimed to evaluate the association between high-intensity staffing by a dedicated cardiac intensivist and clinical outcomes in CS.
Methods:
We enrolled 2923 consecutive patients admitted to a cardiac care unit (CCU) from January 1, 2012 to December 31, 2015. In January 2013, the CCU changed from a low-intensity to high-intensity staffing unit managed by a dedicated cardiac intensivist. Patients were eligible if they required inotropes or vasopressors to maintain a systolic blood pressure>90mmHg, and had serum lactate≥2.0mmol/L. Eligible patients (n=513) were treated by low-intensity CCU (n=352) or high-intensity CCU (n=161). The primary outcome was CCU mortality.
Results:
CCU mortality occurred in 49 patients (30.6%) of the low-intensity group versus 62 patients (17.6%) of the high-intensity group (adjusted odds ratio [aOR] 0.44, 95% confidence interval [CI] 0.25-0.75, p<0.001). In-hospital mortality was not significantly different between the groups (33.1% vs 24.4%, aOR 0.75, 95% CI 0.43-1.29, p=0.29). Among 135 patients treated with extracorporeal membrane oxygenation, the high-intensity model was associated with lower CCU mortality (54.5% vs 22.5%, aOR 0.24, 95% CI 0.07-0.77, p=0.02) and in-hospital mortality (57.6% vs 29.4%, aOR 0.28, 95% CI 0.10-0.81, p=0.02).
Conclusion:
High-intensity staffed CCU managed by a dedicated cardiac intensivist was associated with a significant reduction of CS-related mortality.
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