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Synthetic scale-up of a novel fluorescent probe and its biological evaluation for surface detection of Staphylococcus
Luke Bywaters1, Lauren Mulcahy-Ryan2, Mark Fielder2
1Chemistry and Pharmaceutical Sciences, SEC Faculty, Kingston University, Kingston-upon-Thames KT1 2EE, United Kingdom.
Molecular and Cellular Probes
|July 3, 2017
Abstract:
This paper reports on the LGX fluorometric test for enzymatic MRSA/MSSA detection. It highlights the reasons rhodamines have been overlooked and also strategies to improve the synthesis of rhodamine-peptide conjugates. Evaluation of the LGX test for detection of MRSA/MSSA on surfaces is undertaken in the presence of potentially confounding E. coli and S. epidermidis for the first time.
