Related Experiment Video
Updated: Feb 27, 2026

07:57
A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
22.5K
Mapping the relationship between anxiety, anhedonia, and depression
E Samuel Winer1, Jessica Bryant1, Gregory Bartoszek2
1Department of Psychology, Mississippi State University, P.O. Box 6161, Mississippi State, MS 39762, USA.
Journal of Affective Disorders
|July 3, 2017
Summary
Anhedonia, the inability to experience pleasure, may link anxiety and depression. This study suggests anxiety can lead to anhedonia, which then contributes to depression over time.
Area of Science:
- Psychiatry
- Clinical Psychology
- Behavioral Science
Background:
- Anxiety and depression frequently co-occur, but the developmental pathways are not fully understood.
- Anhedonia, characterized by a loss of pleasure, is hypothesized as a potential mediator in this comorbidity.
Purpose of the Study:
- To investigate the role of anhedonia as a linking factor between anxiety and depression.
- To examine the temporal relationship between anxiety, anhedonia, and depression.
Main Methods:
- Three studies were conducted involving participants assessing symptoms of anxiety, depression, anhedonia, and related constructs.
- Study 1 utilized cross-sectional data from 109 participants.
- Studies 2 and 3 involved larger samples (N=747 and N=216, respectively) with Study 3 employing longitudinal data collection over 11 months.
Main Results:
- Anxiety and depression were linked in individuals avoiding activities due to anxiety, with anhedonia partially explaining this relationship in Study 2.
- Study 3 demonstrated that anxiety predicted anhedonia and subsequent depression, and anhedonia predicted anxiety and subsequent depression over time.
Conclusions:
- Anhedonia appears to be a significant mediator in the development of depression from anxiety.
- Anxious individuals may experience a loss of pleasure in activities, leading to the onset of depressive symptoms.
Related Concept Videos
Anxiety: Overview
1.2K
Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
1.2K
Self-Discrepancy and Its Effects
366
Self-discrepancy theory explains how people compare their actual self to their ideal and ought selves and how mismatches between these self-guides can lead to emotional distress. Developed by E. Tory Higgins, the theory distinguishes among three components of self-concept: the actual self, the ideal self, and the ought self. These refer respectively to how individuals perceive themselves, how they aspire to be, and how they believe they are obligated to be. Emotional well-being, self-esteem,...
366
Depressive Disorders: MDD and Dysthymia
911
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
911
Depressive Disorders: Etiology
793
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
793
Depression: Overview
1.1K
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
1.1K
Generalized Anxiety Disorder
859
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
859

