Related Experiment Video
Updated: Feb 27, 2026
Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Radiosurgery with a Rotating Gamma System: A Very Effective Treatment for Symptomatic Cerebral Cavernomas
Pham Cam Phuong1, Nguyen Duc Luan2, Vo Thi Huyen Trang2
1The Nuclear Medicine and Oncology Center, Bach Mai Hospital, Hanoi, Vietnam phamcamphuong@gmail.com.
Aim:
To evaluate the value of radiosurgery with a rotating gamma-system (RGS) for cerebral cavernomas.
Patients And Methods:
Seventy-nine patients with symptomatic cerebral cavernomas underwent RGS radiosurgery at the Bach Mai Hospital, Hanoi, Vietnam. Median dose (single fraction) was 20 Gy (range=14-26 Gy). Endpoints included effect on headache, seizures and tumor size.
Results:
Of 60 patients with headache, 17% had complete response, 82% partial response and 2% stable disease (best response). Of 39 patients with seizures, 31% had complete response, 64% partial response and 5% stable disease. Four patients developed recurrent seizures after 1 year. Regarding the size of cavernoma at 15 months, complete response was observed in 6%, partial response in 75%, stable disease in 15%, progression in 1% and pseudo-progression in 3% of patients. Bleeding within 2 years after RGS radiosurgery occurred in only five patients (6%). RGS dose had no significant impact on outcomes.
Conclusion:
RGS radiosurgery provided very high rates of symptom relief in patients with cerebral cavernomas.
