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Cardiorenal Syndrome: Diagnosis and Management

João S Orvalho1, Larry D Cowgill2

  • 1University of California Veterinary Medical Center - San Diego, 10435 Sorrento Valley Road, Suite 101, San Diego, CA 92121, USA.

The Veterinary Clinics of North America. Small Animal Practice
|July 4, 2017
PubMed

Insights

Cardiorenal syndrome (CRS) in pets is poorly understood but crucial for treatment. Improved awareness and new biomarkers offer better diagnosis and management of this heart and kidney condition.

Area of Science:

  • Veterinary Medicine
  • Cardiology
  • Nephrology

Background:

  • Cardiorenal syndrome (CRS) involves complex interactions between the heart and kidneys.
  • Understanding CRS is vital for improving clinical outcomes in veterinary patients.
  • Recent efforts have focused on establishing consensus for cardiovascular-renal axis disorders in dogs and cats.

Purpose of the Study:

  • To highlight the importance of characterizing cardiorenal syndrome in veterinary medicine.
  • To emphasize the clinical implications of understanding the cardiovascular-renal axis.
  • To discuss the potential of biomarkers in diagnosing and managing CRS.

Main Methods:

  • Review of current understanding of cardiorenal syndrome in veterinary medicine.
  • Discussion of a recently attempted consensus on cardiovascular-renal axis disorders.
  • Exploration of the role of organ-specific biomarkers.

Main Results:

  • Cardiorenal syndrome is not well-characterized in veterinary medicine.
  • A consensus for cardiovascular-renal axis disorders in dogs and cats has been attempted.
  • Increased awareness and understanding of CRS pathophysiology are expected to improve patient outcomes.

Conclusions:

  • Accurate appreciation of the heart-kidney interaction is clinically significant.
  • Emerging organ-specific biomarkers offer enhanced diagnostic and management capabilities for cardiac disease.
  • Improved identification and understanding of CRS pathophysiology are key to better patient outcomes.

Keywords:
BiomarkersCardiorenal syndromeCardiovascular-renal axis disordersChronic kidney diseaseHeart failure

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