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Updated: Feb 27, 2026
Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
Published on: June 7, 2019
Two cancers in one: breast carcinoma with underlying melanoma
Nicholas A Douville1, Elizabeth A Sakach1, Elizabeth A Wiewiorowski1
1Texas A&M Health Science Center College of Medicine (Douville, Sakach, Wiewiorowski, Pippen); the Departments of Pathology (Herlihy) and Oncology (Pippen), Baylor University Medical Center at Dallas; and Texas Oncology (Pippen), Dallas, Texas.
Abstract:
A 61-year-old woman presented with a diagnosis of metastatic invasive lobular carcinoma of the right breast, and after treatment it had regressed or was stable except for a scalp nodule. When biopsied, the outer edges of the scalp lesion had findings consistent with breast carcinoma; however, the bulk of the tumor's pathology was consistent with melanoma. It appeared that most of the tumor was a highly vascularized melanoma with lobular breast carcinoma noted at its edges.
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