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Updated: Feb 27, 2026

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
Mixed phenotypic acute leukemia with leukemia cutis and neuroleukemiosis
Rona Joseph Poikayil1, Geetha Narayanan1, Harish Sugathan1
1Department of Medical Oncology, Regional Cancer Centre, Trivandrum, India.
Abstract:
Leukemia cutis and neuroleukemiosis are two rare extramedullary manifestations of acute leukemia. We report a 32-year-old woman with multiple skin lesions and painful peripheral neuropathy. Bone marrow biopsy and skin biopsy confirmed the diagnosis of mixed phenotypic acute leukemia. After induction chemotherapy, she attained marrow remission, her skin lesion resolved completely, and her neurologic symptoms significantly improved.

