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Updated: Feb 27, 2026

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Published on: February 12, 2022
B-lymphoblastic lymphoma of the rectum
Puthillathu Unnikrishnan1, Geetha Narayanan1, Bhavya S Kumar1
1Department of Medical Oncology, Regional Cancer Center, Trivandrum 695011, India.
Abstract:
Lymphoblastic lymphoma is a neoplasm of immature cells committed to the B-cell or T-cell lineage. B-lymphoblastic lymphoma usually involves lymph nodes and extranodal sites, such as the skin, bone, and soft tissue. The rectum is a very rare site of involvement in B-lymphoblastic lymphoma. We describe a 26-year-old man who presented with bleeding per rectum and fecal incontinence. Endoscopy showed a large nodular friable lesion narrowing the entire rectal lumen. Biopsy was diagnostic of B-lymphoblastic lymphoma. He was started on chemotherapy with the Berlin-Frankfurt-Münster protocol and achieved complete remission after induction chemotherapy. This is the first report of B-lymphoblastic lymphoma presenting as a rectal lesion in the world literature.
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