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Plasmapheresis for recurrent acute pancreatitis from hypertriglyceridemia
Kathleen Kopecky1, Amber Moreland1, Christopher Hebert1
1Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas.
Proceedings (Baylor University. Medical Center)
|July 4, 2017
Summary
Plasmapheresis effectively treated severe hypertriglyceridemia causing acute pancreatitis in a recurrent case. This rapid triglyceride reduction offers a life-saving intervention for similar critical presentations.
Area of Science:
- Endocrinology
- Gastroenterology
- Critical Care Medicine
Background:
- Severe hypertriglyceridemia is a critical cause of acute pancreatitis.
- Plasmapheresis is an underreported but potentially life-saving therapy for hypertriglyceridemic pancreatitis.
- Recurrent episodes pose significant management challenges.
Observation:
- A 38-year-old obese Hispanic woman presented with acute pancreatitis secondary to diabetic hypertriglyceridemia.
- She had a history of similar pancreatitis within the same year.
- Prompt initiation of plasmapheresis was performed.
Findings:
- One plasma volume exchange resulted in a 74% reduction in triglyceride levels.
- A second session led to a total triglyceride reduction of 93%.
- The patient responded favorably to plasmapheresis on both occasions.
Implications:
- Plasmapheresis is a highly effective treatment for acute pancreatitis caused by severe hypertriglyceridemia.
- This case highlights the successful use of plasmapheresis in recurrent hypertriglyceridemic pancreatitis.
- Prompt plasmapheresis should be considered in life-threatening hypertriglyceridemic pancreatitis presentations.
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