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Updated: Feb 27, 2026

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
Published on: February 12, 2011
Left ventricular myocardial strain in ventricular arrhythmia without structural heart disease using cardiac magnetic
Xuepei Tang1, Sisi Yu1, Yaohan Yu1
1Department of MRI, The Second Affiliated Hospital of Nanchang UniversityNanchang, Jiangxi, China.
Insights
Ventricular arrhythmia (VA) in structurally normal hearts can impair left ventricular (LV) function. Cardiac magnetic resonance feature tracking (CMR-FT) effectively detects abnormal LV myocardial strain in VA patients, indicating potential for early intervention.
Area of Science:
- Cardiology
- Medical Imaging
- Biomedical Engineering
Background:
- Ventricular arrhythmias (VA) in structurally normal hearts were considered benign.
- Recent evidence suggests VA can induce left ventricular (LV) dysfunction.
- No effective methods currently exist to detect abnormal myocardial systolic function in VA patients.
Purpose of the Study:
- To investigate LV myocardial strain in VA patients using cardiac magnetic resonance feature tracking (CMR-FT).
- To assess the efficacy of CMR-FT in detecting systolic function abnormalities in VA patients without known heart disease.
Main Methods:
- Utilized CMR-FT on balanced steady-state free precession (SSFP) cine images.
- Analyzed LV myocardial strain in 42 VA patients and 29 healthy volunteers.
- Compared peak strain values (radial, circumferential, longitudinal) and segmental strain patterns between groups.
Main Results:
- VA patients exhibited lower peak radial and circumferential strain in basal and middle LV segments compared to controls.
- Longitudinal strain was decreased in the middle LV segments of VA patients.
- Reduced strain was more pronounced in anterior, inferoseptal, and anterolateral segments, particularly in patients with frequent premature ventricular complexes.
Conclusions:
- VA in structurally normal hearts is associated with abnormal LV segmental wall motion.
- CMR-FT strain analysis is an effective method for detecting these abnormalities.
- Early clinical management is recommended to prevent symptom progression in VA patients.
Abstract:
Ventricular arrhythmia (VA) in structurally normal heart is considered as benign. However, these arrhythmias have been recently reported to induce left ventricular (LV) dysfunction. Up to now, there is no efficacious method to detect abnormal myocardial systolic function in VA patients. Therefore, in the current study, we used cardiac magnetic resonance feature tracking (CMR-FT) on balanced steady state free precision (SSFP) cine images to investigate LV myocardial strain in 42 VA patients without known heart disease as well as in 29 normal volunteers. As compared with controls, VA patients had lower peak values of radial and circumferential strain (RS, CS) in both basal and middle parts of LV and the peak value of longitudinal strain (LS) in VA patients was also decreased in middle LV. Moreover, as revealed by LV myocardial segmental peak strain, reduced RS, CS and LS peaks in VA were more significant in anterior, inferoseptal and anterolateral segments, especially for the patients with frequent premature ventricular complexes. Our results suggested that VA in normal heart is associated with abnormal segmental wall motion, which can be efficaciously detected by CMR-FT derived strain analysis. And early clinical management should be considered to prevent further significant symptoms in these patients.
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