Left ventricular myocardial strain in ventricular arrhythmia without structural heart disease using cardiac magnetic

Xuepei Tang1, Sisi Yu1, Yaohan Yu1

  • 1Department of MRI, The Second Affiliated Hospital of Nanchang UniversityNanchang, Jiangxi, China.

Insights

Ventricular arrhythmia (VA) in structurally normal hearts can impair left ventricular (LV) function. Cardiac magnetic resonance feature tracking (CMR-FT) effectively detects abnormal LV myocardial strain in VA patients, indicating potential for early intervention.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Ventricular arrhythmias (VA) in structurally normal hearts were considered benign.
  • Recent evidence suggests VA can induce left ventricular (LV) dysfunction.
  • No effective methods currently exist to detect abnormal myocardial systolic function in VA patients.

Purpose of the Study:

  • To investigate LV myocardial strain in VA patients using cardiac magnetic resonance feature tracking (CMR-FT).
  • To assess the efficacy of CMR-FT in detecting systolic function abnormalities in VA patients without known heart disease.

Main Methods:

  • Utilized CMR-FT on balanced steady-state free precession (SSFP) cine images.
  • Analyzed LV myocardial strain in 42 VA patients and 29 healthy volunteers.
  • Compared peak strain values (radial, circumferential, longitudinal) and segmental strain patterns between groups.

Main Results:

  • VA patients exhibited lower peak radial and circumferential strain in basal and middle LV segments compared to controls.
  • Longitudinal strain was decreased in the middle LV segments of VA patients.
  • Reduced strain was more pronounced in anterior, inferoseptal, and anterolateral segments, particularly in patients with frequent premature ventricular complexes.

Conclusions:

  • VA in structurally normal hearts is associated with abnormal LV segmental wall motion.
  • CMR-FT strain analysis is an effective method for detecting these abnormalities.
  • Early clinical management is recommended to prevent symptom progression in VA patients.

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