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Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
A screening echocardiogram to identify diastolic dysfunction leads to better outcomes
Reyan Ghany1, Ana Palacio2,3, Gordon Chen1
1Chen Senior Medical Centers, Miami, FL, USA.
Insights
Screening echocardiograms found moderate-to-severe diastolic dysfunction (DD) in 27% of seniors. Identifying DD in older adults improves heart failure care and medication management.
Area of Science:
- Cardiology
- Geriatric Medicine
- Diagnostic Imaging
Background:
- Diastolic dysfunction (DD) is a precursor to heart failure and increased mortality.
- Echocardiography detects DD but is not routinely recommended for screening in older adults.
- This study evaluated the prevalence and clinical impact of DD screening in seniors.
Purpose of the Study:
- To determine the prevalence of diastolic dysfunction in an elderly population.
- To assess the impact of identifying DD on heart failure management in seniors.
- To evaluate the effectiveness of screening echocardiograms in value-based senior care settings.
Main Methods:
- A screening echocardiogram was performed on 5227 consecutive patients across 36 senior-focused clinics.
- Diastolic dysfunction was graded, and patients were classified as asymptomatic (Stage B) or symptomatic (Stage C).
- Changes in heart failure medication prescriptions before and after echocardiography were analyzed.
Main Results:
- The prevalence of moderate-to-severe DD (Grade 2-3) with preserved ejection fraction was 25%.
- Among patients with moderate-to-severe DD, 27% were symptomatic (Stage C).
- Prescription of ace-inhibitors, beta-blockers, statins, and diuretics increased post-echocardiogram, particularly in symptomatic DD patients.
Conclusions:
- A significant portion of seniors without prior heart failure diagnosis exhibit moderate-to-severe diastolic dysfunction.
- Screening for DD in older adults can lead to improved heart failure therapy and patient care.
- Early identification of DD in seniors is crucial for proactive management and better health outcomes.
Background:
Diastolic dysfunction (DD) can lead to heart failure and higher mortality. Echocardiograms can detect DD but are not indicated for screening in older adults. Our aim was to evaluate the prevalence of DD and the impact of identifying it in seniors.
Methods:
We performed screening echocardiograms in 5227 consecutive patients between January 2014 and March 2015 in 36 senior-focused value-based clinics across six states. We determined the presence of the grade of DD and defined stage B grade II/III (asymptomatic) and of stage C grade II/III (symptomatic) DD by the presence or absence of typical HF symptoms. We obtained prescribed medications from the electronic health record to determine absolute changes in HF therapy before and after the echocardiogram.
Results:
We included a group with no DD (n=649), a group with grade 1 DD (n=2875), and those with grades 2 and 3 (n=1357) who had normal ejection fraction. The prevalence of grade 2 or 3 DD with preserved ejection fraction was 25%; 95% CI: 24-26. The absolute change of ace-inhibitor use before and after the echocardiogram increased by 14, 19, 23, 27 in patients without DD, those with grade 1, grade 2 or 3 asymptomatic and grade 2 or 3 symptomatic, respectively. The use of β-blocker, statin, and diuretic had similar trends.
Conclusions:
Seniors without previously known stage B or stage C heart failure have moderate-to-severe DD, 27% of whom were stage C. Identifying seniors with DD leads to improvement in care.
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