Factors related to retinal haemorrhage in infants born at high risk

Qinglan Pu1, Ping Li1, Huiqin Jiang1

  • 1Department of Ophthalmology, Jiaxing Maternal and Child health care Hospital, Jiaxing, Zhejiang, China.

Insights

Retinal haemorrhage (RH) affects 18% of high-risk infants. Delivery mode and neonatal asphyxia are identified as significant risk factors for developing RH in these vulnerable newborns.

Area of Science:

  • Ophthalmology
  • Neonatology
  • Perinatology

Background:

  • Retinal haemorrhage (RH) is a known complication in newborns.
  • Identifying risk factors is crucial for prevention and management in high-risk infants.

Purpose of the Study:

  • To determine the incidence of retinal haemorrhage (RH) in high-risk infants.
  • To identify specific risk factors associated with RH development in this population.

Main Methods:

  • A cohort of 3123 high-risk infants (due to high-risk pregnancy and/or neonatal asphyxia) were studied.
  • Fundus examinations were conducted using a wide-angle imaging system (RetCam III).
  • Maternal, obstetric, and neonatal parameters were compared between infants with and without RH.

Main Results:

  • The incidence of RH was 18% (550/3123 infants).
  • RH was graded I (39%), II (24%), and III (37%).
  • Delivery mode and neonatal asphyxia were identified as significant risk factors for RH.

Conclusions:

  • The incidence of RH in high-risk infants is 18%.
  • Delivery mode and neonatal asphyxia are major risk factors for RH.
  • Early identification and intervention strategies targeting these factors are warranted.
Abstract