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Protein Dynamics in Living Cells

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Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
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Related Experiment Video

Updated: Feb 27, 2026

DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering
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Analyzing Spin Selectivity in DNA-Mediated Charge Transfer via Fluorescence Microscopy.

John M Abendroth, Nako Nakatsuka, Matthew Ye

  • 1Center for Memory and Recording Research, University of California, San Diego , La Jolla, California 92093, United States.

ACS Nano
|July 4, 2017
PubMed
Summary

Chiral-induced spin selectivity was observed in DNA on magnetic surfaces. External magnetic fields modulated spin-dependent charge transport, affecting fluorescence.

Keywords:
DNA-mediated charge transferchemical lift-off lithographychiral-induced spin selectivity effectfluorescence microscopyperylenediimidephotospintronics

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Area of Science:

  • Molecular Biophysics
  • Spintronics
  • Surface Science

Background:

  • Electron spin plays a crucial role in biological systems.
  • Chiral molecules and their spin-selective interactions are key for organic spintronics.
  • Chiral-induced spin selectivity (CISS) is a phenomenon where electron spin is filtered by chiral materials.

Purpose of the Study:

  • To visualize spin-dependent charge transport in DNA on ferromagnetic substrates.
  • To quantify the influence of substrate magnetization on fluorescence via the CISS effect.
  • To investigate the modulation of DNA-mediated charge transfer by external magnetic fields.

Main Methods:

  • Utilizing fluorescence microscopy to observe spin-selective interactions.
  • Employing self-assembled monolayers of double-stranded DNA on patterned ferromagnetic substrates.
  • Applying external magnetic fields to control substrate magnetization orientation.

Main Results:

  • Demonstrated spin-dependent charge transport in DNA monolayers.
  • Quantified magnetization-dependent fluorescence quenching linked to the CISS effect.
  • Showcased modulation of DNA-mediated charge transfer by magnetic field switching.

Conclusions:

  • The study provides visual evidence of CISS in DNA systems.
  • Results highlight the tunability of spin-selective charge transport in DNA-based spintronics.
  • Confirms the potential of DNA assemblies for spintronic applications.