EASApprox® skin-stretching system: A secure and effective method to achieve wound closure
Mingzhi Song1,2, Zhen Zhang1, Tao Liu1
1Department of Orthopedics, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China.
Experimental and Therapeutic Medicine
|July 5, 2017
Summary
The EASApprox® skin-stretching system effectively manages large skin defects. This innovative device shows potential for wound healing with minimal impact on skin histology and microcirculation.
Area of Science:
- Biomedical Engineering
- Dermatology
- Wound Healing Research
Background:
- Large skin defects present a significant clinical challenge globally.
- Effective wound closure solutions for extensive skin loss are in high demand.
Purpose of the Study:
- To evaluate the efficacy of the EASApprox® skin-stretching system for closing large skin defects.
- To compare the EASApprox® system against traditional methods like direct suture and Kirschner wires.
Main Methods:
- Creation of 5x5 cm skin defects in Bama miniature pigs.
- Random assignment to three groups: direct suture, EASApprox® device, and Kirschner wires.
- Assessment of microcirculation, clinical healing scores, and histological analysis (collagen, elastic fibers, microvessel density).
Main Results:
- Significant differences observed in clinical scores and microvessel density across groups.
- The EASApprox® group showed a larger mean elastic fiber length compared to controls.
- Successful wound management with the EASApprox® system, demonstrating minimal side effects.
Conclusions:
- The EASApprox® skin-stretching device offers a promising solution for managing large skin defects.
- This method exhibits potential for improved wound healing outcomes with good histological and microcirculatory profiles.
