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Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation
Published on: February 15, 2018
Feeding of preterm infants and fortification of breast milk
Giovanna Mangili1, Elena Garzoli
1Local Health Unit Papa Giovanni XXIII, Bergamo. gmangili@asst-pg23.it.
Insights
Optimal nutrition is crucial for infant growth and development. Early nutritional strategies, including parenteral and enteral methods, are vital for very low birth weight (VLBW) infants to prevent growth delays.
Area of Science:
- Neonatal nutrition
- Pediatric growth and development
Background:
- Adequate nutrient administration supports linear growth and neurocognitive development.
- Extra-uterine growth delay is a concern in very low birth weight (VLBW) infants.
- Timely nutritional strategies are essential from the first day of life.
Purpose of the Study:
- To highlight the importance of rapid nutritional support in VLBW infants.
- To discuss parenteral and enteral nutrition options for preterm infants.
- To address nutritional challenges in premature infants.
Main Methods:
- Review of current nutritional strategies for preterm and VLBW infants.
- Discussion of parenteral nutrition indications in prematurity.
- Evaluation of enteral nutrition choices, including breast milk and alternatives.
Main Results:
- Parenteral nutrition is frequently indicated in preterm infants due to immature digestive systems and low reserves.
- Breast milk is the preferred enteral source, often requiring fortification for VLBW infants.
- Specialized infant formulas serve as an alternative when breast milk is unavailable.
Conclusions:
- Rapid implementation of appropriate nutrition, parenteral or enteral, is key to improving outcomes for VLBW infants.
- Addressing protein and mineral deficits is critical for preterm infants.
- Tailored nutritional support is essential for optimal infant development.
Abstract:
The administration of the adequate amount of nutrients helps to improve a correct short-term linear growth and long-term neurocognitive development. To reduce the extra-uterine growth delay in very low birth weight infants (VLBW) the best strategy of nutrition (parenteral or enteral) should be established rapidly, since the first day of life. In preterm infants, nutrition can be administered parenterally and enterally. Prematurity is the most frequent indication for parenteral nutritional support due to intestinal functional immune deficiency, deficiency of digestive enzymatic systems and reduced nutritional reserve of these infants. In terms of enteral nutrition, breast milk is the first choice. In case of preterm and VLBW infants, fortifiers are used to overcome breast milk's protein and mineral deficiencies. When breast milk is not available, specific infant formula is the alternative.
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