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Updated: Feb 27, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
[Proteus mirabilis septic arthritis]
Mohammed Sbiti1,2, Bahia Bouhamidi3, Lhoussaine Louzi1,4
1Service de Microbiologie, Hôpital Militaire Moulay Ismail Meknès, Maroc.
Abstract:
Acute septic arthritis is rare. It is associated with poor prognosis in terms of mortality and morbidity. We report the case of a 61-year old patient with spontaneous Proteus mirabilis septic arthritis. He suffered from complicated diabetes associated with positive blood cultures and synovial fluid cultures. Patient's evolution was favorable thanks to early diagnosis and initiation of adequate antibiotic therapy. Proteus mirabilis septic arthritis is rare. On that basis we conducted a literature review of cases of Proteus mirabilis pyogenic arthritis to highlight the risk factors, pathogenesis, treatment and evolution of these diseases. Diagnosis is commonly based on microbiological analysis, early articular puncture biopsy is performed before the initiation of antibiotic treatment, direct examination, culture and antibiogram which are useful as guidance for antibiotic therapy. Septic arthritis is a diagnostic and therapeutic emergency; early management of this disease allows total healing without after-effects.
Insights
Acute septic arthritis, though rare, carries a high risk. Early diagnosis and antibiotic treatment of Proteus mirabilis septic arthritis are crucial for favorable outcomes and preventing long-term complications.
Area of Science:
- Infectious Diseases
- Rheumatology
- Microbiology
Background:
- Septic arthritis is a severe joint infection with significant mortality and morbidity risks.
- Proteus mirabilis septic arthritis is an uncommon presentation requiring specific clinical attention.
Observation:
- A 61-year-old male with complicated diabetes developed spontaneous Proteus mirabilis septic arthritis.
- The patient presented with positive blood and synovial fluid cultures, indicating systemic infection.
Findings:
- Prompt diagnosis and appropriate antibiotic therapy led to a favorable clinical outcome.
- Literature review highlighted risk factors, pathogenesis, and treatment strategies for Proteus mirabilis septic arthritis.
- Microbiological analysis, including synovial fluid culture and antibiogram, is key for guiding therapy.
Implications:
- Early recognition and management of septic arthritis are essential for complete healing and avoiding sequelae.
- This case underscores the importance of considering rare pathogens in septic arthritis, especially in immunocompromised patients.
- Effective antibiotic stewardship based on microbiological data is vital for successful treatment.
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