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[Relationship between oral and gut microbes].

Cheng Xingqun1, Xu Xin1, Zhou Xuedong1

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Hua Xi Kou Qiang Yi Xue Za Zhi = Huaxi Kouqiang Yixue Zazhi = West China Journal of Stomatology
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Summary

This review explores the oral cavity and gut microbial communities, detailing their structures, functions, and interactions. It examines how these microbes cause disease and their links to systemic health conditions.

Keywords:
gutmicrobiomeoral cavitysystemic diseases

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Area of Science:

  • Microbiology
  • Gastroenterology
  • Human Health

Background:

  • The oral cavity and gut are crucial components of the digestive system.
  • Microbial communities in these areas have been widely studied for structure and pathogenesis.
  • Interactions and pathogenic effects of oral and gut microbiota are areas of significant research.

Purpose of the Study:

  • To integrate existing literature on oral and gut microbial communities.
  • To discuss the structures and functions of these microbial ecosystems.
  • To explore the mutual colonization, pathogenesis, and systemic disease links of oral and gut microbes.

Main Methods:

  • Literature review and data integration.
  • Analysis of microbial community structures and functions.
  • Examination of pathogenic mechanisms and disease associations.

Main Results:

  • Detailed descriptions of oral and gut microbial community compositions.
  • Elucidation of the functional roles of these microbes.
  • Identification of pathogenic interactions between oral and gut microbes.
  • Established links between microbial dysbiosis and systemic diseases.

Conclusions:

  • The oral cavity and gut harbor complex microbial communities with significant health implications.
  • Understanding the interplay between oral and gut microbiota is key to addressing associated systemic diseases.
  • Further research into microbial interactions can lead to novel therapeutic strategies.