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Updated: Feb 27, 2026

Frailty Assessment in an Aging Mouse Model
Published on: September 23, 2025
Relationship between perceptions of ageing and frailty in English older adults
Krystal Warmoth1,2, Mark Tarrant1,2, Charles Abraham1,2
1a Collaboration for Leadership in Applied Health Research and Care South West Peninsula , Exeter , UK.
Abstract:
Older adults' negative beliefs about ageing are related to their health and functioning, but little is known about how perceptions of ageing (POA) relate to frailty status. This study aimed to explore the relationship between POA and frailty. Secondary analysis of data used were from the English Longitudinal Study of Ageing Waves 2 and 5. A POA score was based on participants' responses to 12 statements using a five-point Likert scale at baseline, and a Frailty Index (FI) score was calculated for each participant for both waves. Multiple linear regression models were conducted to assess the relationship between POA and frailty cross-sectionally and longitudinally in models controlled for age, gender, depression symptoms, and socioeconomic status. Older adults with more negative POA had greater frailty (β = .12, p < .001). Negative POA predicted greater frailty 6 years later (β = .03, p < .05). Future work regarding the mechanisms of this relationship is needed to identify ways of intervening to improve health.
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