Related Experiment Video
Updated: Feb 27, 2026

05:43
An In Vitro Assay to Study Platelet Migration Using RGD-Functionalized Avidin-Biotin Tethers
Published on: November 8, 2024
865
Corrigendum: Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα
Nature Communications
|July 5, 2017
Summary
This article corrects the Digital Object Identifier (DOI) for a previously published study. The correction ensures accurate referencing and retrieval of the scientific research. This ensures proper citation for the scientific community.
Area of Science:
- Scientific Publishing
- Scholarly Communication
- Research Integrity
Background:
- Accurate referencing is crucial for scientific integrity.
- Digital Object Identifiers (DOIs) ensure persistent access to research.
- Previous publications may contain errors requiring correction.
Purpose of the Study:
- To correct an erroneous Digital Object Identifier (DOI).
- To ensure accurate citation and retrieval of a specific scientific article.
- To maintain the integrity of the scientific record.
Main Methods:
- Identification of the incorrect DOI.
- Verification of the correct DOI.
- Formal correction submission to the publishing platform.
Main Results:
- The incorrect DOI has been identified and rectified.
- The correct DOI is now associated with the article.
- Ensured accurate linkage to the scientific work.
Conclusions:
- The correction enhances the reliability of scientific literature.
- Accurate DOIs facilitate seamless access to research findings.
- This ensures the scientific community can properly cite and access the work.
More Related Videos
Related Concept Videos
Intracellular Signaling Affects Focal Adhesions
3.7K
Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
Some...
Some...
3.7K
Activation of Integrins
5.3K
Integrins bind ligands and transmit information from outside the cell to inside or vice-versa through an "outside-in signaling" or "inside-out signaling."
In "outside-in signaling," external factors in the extracellular space bind to exposed ligand binding sites on integrins. This causes the inactive protein to undergo a conformational change to become active. Integrins are often clustered on the cell membrane. Repetitive and regularly spaced ligand binding...
In "outside-in signaling," external factors in the extracellular space bind to exposed ligand binding sites on integrins. This causes the inactive protein to undergo a conformational change to become active. Integrins are often clustered on the cell membrane. Repetitive and regularly spaced ligand binding...
5.3K
Integrins
5.8K
Animal and protozoan cells do not have cell walls to help maintain shape and provide structural stability. Instead, these eukaryotic cells secrete a sticky mass of carbohydrates and proteins into the spaces between adjacent cells. This network of proteins and molecules is called an extracellular matrix or ECM.
Some ECM proteins assemble into a basement membrane to which the remaining components adhere. Proteoglycans typically form the bulk of the ECM while fibrous proteins, like collagen,...
Some ECM proteins assemble into a basement membrane to which the remaining components adhere. Proteoglycans typically form the bulk of the ECM while fibrous proteins, like collagen,...
5.8K
Selectins
4.6K
Cell adhesion is an essential aspect of multicellularity. While stable cell interactions usually occur between cells of the same type, transient cell interactions occur between cells of different tissue types, such as between neutrophils and endothelial cells. Selectins are one class of cell adhesion molecules (CAMs) that bind carbohydrate ligands to form transient cell adhesion. They are rod-like proteins with a long extracellular part of variable length ending with the lectin domain,...
4.6K
Formation of the Platelet Plug
10.0K
The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
10.0K
Structure and Function of Platelets
4.1K
The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000...
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000...
4.1K

