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Psoriasiform graft-versus-host disease distributed along Blaschko's lines
Philip B Milam1, Sumithra V Vasu2, Alejandro A Gru3
1Department of Internal Medicine, Division of Dermatology, Ohio State University Wexner Medical Center, Gahanna, Ohio.
Journal of Cutaneous Pathology
|July 5, 2017
Summary
Cutaneous chronic graft-vs-host disease (cGVHD) can mimic psoriasis along Blaschko's lines, posing a diagnostic challenge. This rare presentation in transplant patients warrants consideration, potentially revealing underlying mosaicism.
Area of Science:
- Dermatology
- Immunology
- Transplantation Medicine
Background:
- Cutaneous chronic graft-vs-host disease (cGVHD) is a significant complication post-hematopoietic stem cell transplantation.
- cGVHD can present with diverse dermatological manifestations, sometimes mimicking other common skin conditions.
- Psoriasis is a well-known inflammatory skin condition with distinct clinical and histopathological features.
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