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3D bioprinting and the current applications in tissue engineering.

Ying Huang1, Xiao-Fei Zhang1, Guifang Gao1

  • 1School of Chemistry, Chemical Engineering and Life Sciences, School of Materials Science and Engineering, Wuhan University of Technology, 122 Luoshi Rd, Wuhan, Hubei, China.

Biotechnology Journal
|July 5, 2017
PubMed
Summary

Bioprinting enables precise fabrication of tissues and organs for medicine and research. This review covers techniques, bioinks, applications, and future potential in regenerative medicine and drug discovery.

Keywords:
BiomaterialsBioprintingStem cellsTissue engineeringTranslational medicine

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Area of Science:

  • Bioprinting and Tissue Engineering
  • Regenerative Medicine
  • Biomaterials Science

Background:

  • Bioprinting is a key biofabrication technology for creating engineered tissues and organs.
  • It offers high throughput and precise control over scaffolds and cells, crucial for translational medicine and research.
  • Current applications include constructing functional tissues like vasculature, muscle, cartilage, and bone.

Purpose of the Study:

  • To review popular bioprinting techniques and processes.
  • To describe bioink composition, including scaffolds and cells.
  • To introduce current applications and discuss future potential and challenges in organ and tissue bioprinting.

Main Methods:

  • Review of existing literature on bioprinting techniques, processes, and materials.
  • Analysis of current applications in tissue and organ fabrication.
  • Discussion of challenges and future directions, including automation and biomaterial integration.

Main Results:

  • Bioprinting utilizes various techniques to fabricate complex tissue structures from medical images.
  • It serves as an efficient tool for drug discovery and preclinical testing.
  • The technology has the potential for direct patient treatment through automated, site-specific repair devices.

Conclusions:

  • Bioprinting is a versatile technology with broad applications in regenerative medicine and drug development.
  • Future advancements require integration of automation, robotics, biomaterials, and stem cell biology.
  • The ultimate goal is the development of medical devices for direct therapeutic applications in patients.