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Antipsychotic-associated psoriatic rash - a case report
Camelia-Eugenia Bujor1, Torkel Vang2, Jimmi Nielsen1,2,3
1Department of Psychiatry, Aalborg University Hospital, Aalborg, Denmark.
BMC Psychiatry
|July 6, 2017
Summary
This case report explores a potential link between antipsychotic medications and the development of severe psoriasis. Further research is needed to confirm this association and understand the underlying mechanisms.
Area of Science:
- Psychiatry
- Dermatology
- Pharmacology
Background:
- Antipsychotics are diverse medications used to treat psychiatric disorders.
- While effective, antipsychotics can cause unexpected side effects.
- This report investigates a possible association between antipsychotic use and psoriasis.
Observation:
- A 21-year-old female with schizophrenia was treated with quetiapine and then aripiprazole.
- The patient experienced significant weight gain with quetiapine.
- Following the initiation of antipsychotic therapy, she developed severe psoriasis lesions.
Findings:
- The case suggests a potential link between antipsychotic treatment and the onset of severe psoriasis.
- The patient's psoriasis developed after starting antipsychotic medications.
Implications:
- Antipsychotics may influence immune responses, potentially triggering immune-mediated conditions like psoriasis.
- Further research is essential to establish causality and elucidate the immunological mechanisms involved.
- This finding may inform clinical practice regarding monitoring for dermatological side effects in patients on antipsychotics.
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