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Updated: Feb 27, 2026
Ischemic Tissue Injury in the Dorsal Skinfold Chamber of the Mouse: A Skin Flap Model to Investigate Acute Persistent Ischemia
Published on: November 17, 2014
The Physiology and Biomechanics of Skin Flaps
1Facial Plastic and Reconstructive Surgery, Carl R. Darnall Army Medical Center, 36065 Santa Fe Avenue, Fort Hood, TX 76544, USA; Department of Surgery, Uniformed Services University of Health Sciences, 4301 Jones Bridge Road #A3007, Bethesda, MD 20814, USA.
Abstract:
Facial skin defects created by Mohs micrographic surgery are commonly reconstructed using local cutaneous flaps from surrounding skin. To provide optimal survival and aesthetic outcomes, the cutaneous surgeon must command a thorough understanding of the complex vascular anatomy and physiology of the skin as well as the imperative physiologic and biomechanical considerations when elevating and transferring tissue via local skin flaps.
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