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Updated: Feb 27, 2026

Designing, Packaging, and Delivery of High Titer CRISPR Retro and Lentiviruses via Stereotaxic Injection
Published on: May 23, 2016
Modeling human disease in rodents by CRISPR/Cas9 genome editing
Marie-Christine Birling1, Yann Herault2,3,4,5,6, Guillaume Pavlovic2
1CELPHEDIA, PHENOMIN, Institut Clinique de la Souris (ICS), CNRS, INSERM, University of Strasbourg, 1 rue Laurent Fries, 67404, Illkirch, France. birlingm@igbmc.fr.
Abstract:
Modeling human disease has proven to be a challenge for the scientific community. For years, generating an animal model was complicated and restricted to very few species. With the rise of CRISPR/Cas9, it is now possible to generate more or less any animal model. In this review, we will show how this technology is and will change our way to obtain relevant disease animal models and how it should impact human health.
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