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Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
Published on: April 7, 2021
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[Acute respiratory distress syndrome : Basic principles and treatment]
P M Spieth1, A Güldner2, M Gama de Abreu2
1Klinik für Anästhesiologie und Intensivtherapie, Pulmonary Engineering Group, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland. peter.spieth@uniklinikum-dresden.de.
Der Anaesthesist
|July 6, 2017
Summary
Acute respiratory distress syndrome (ARDS) remains a significant challenge in intensive care, despite extensive research. Specialized centers offer individualized treatment for ARDS patients, improving outcomes.
Area of Science:
- Critical Care Medicine
- Pulmonology
- Respiratory Medicine
Background:
- Acute respiratory distress syndrome (ARDS) continues to have high mortality rates despite decades of research.
- The complex causes of ARDS make developing new treatments difficult.
- ARDS poses a major challenge for contemporary intensive care units.
Purpose of the Study:
- To highlight the ongoing challenges in ARDS treatment and management.
- To emphasize the importance of specialized care centers for ARDS patients.
Main Methods:
- Review of current therapeutic strategies for ARDS.
- Discussion of lung protective mechanical ventilation.
- Evaluation of adjuvant therapies including prone positioning and extracorporeal lung support.
Main Results:
- Lung protective ventilation, prone positioning, and extracorporeal support are crucial for severe ARDS.
- Treatment in specialized centers leads to individualized and needs-based care.
- Despite advances, ARDS mortality remains a critical issue.
Conclusions:
- Individualized treatment strategies are essential for managing ARDS.
- Specialized centers are vital for optimizing ARDS patient care and outcomes.
- Continued research is necessary to reduce ARDS-related mortality.
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