Related Experiment Video
Updated: Feb 27, 2026
The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model
Published on: January 13, 2023
Comparative, randomized, double-blind clinical study of alveolar ridge preservation using an extracellular
Hyeyoon Chang1, Sulhee Kim1, Jin Wook Hwang2
1Department of Periodontology, Seoul National University School of Dentistry, Seoul, Korea.
Purpose:
The aim of this study was to radiographically and clinically compare the effect of extracellular matrix (ECM) membranes on dimensional alterations following a ridge preservation procedure.
Methods:
One of 2 different ECM membranes was applied during a ridge preservation procedure. A widely used ECM membrane (WEM; Bio-Gide, Geistlich Biomaterials, Wolhusen, Switzerland) was applied in the treatment group and a newly developed ECM membrane (NEM; Lyso-Gide, Oscotec Inc., Seongnam, Korea) was applied in the control group. Cone-beam computed tomography (CBCT) scans and alginate impressions were obtained 1 week and 6 months after the ridge preservation procedure. Results were analyzed using the independent t-test and the nonparametric Mann-Whitney U test.
Results:
There were no significant differences between the ECM membranes in the changes in the dimension, width, and height of the extraction socket or the quantity of bone tissue.
Conclusions:
The NEM showed comparable clinical and radiographic results to the WEM following the ridge preservation procedure.
