Related Experiment Video
Updated: Feb 27, 2026

Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow
Published on: January 13, 2017
Tumescent local anaesthesia for early dermatosurgery in infants
M Heister1, H M Häfner1, H Breuninger1
1Department of Dermatology, Eberhard Karls University, Tübingen, Germany.
Insights
Tumescent local anaesthesia (TLA) combined with paediatric dermatosurgery offers a safe and effective outpatient treatment for infants with small skin lesions. This approach minimizes risks and provides prolonged postoperative pain relief, leveraging infants' natural healing capabilities.
Area of Science:
- Paediatric Dermatology
- Surgical Oncology
- Anaesthesiology
Background:
- Infants exhibit superior skin elasticity and recovery, making early dermatosurgery beneficial for cosmetic outcomes.
- Lesion growth necessitates timely intervention; while some anaesthetics pose risks (e.g., prilocaine causing methaemoglobinemia), many local anaesthetics are safe for infants.
Purpose of the Study:
- To evaluate the safety and efficacy of tumescent local anaesthesia (TLA) followed by dermatosurgery in infants under 7 months.
- To analyze patient records and postoperative survey data for outcomes and complications.
Main Methods:
- Retrospective analysis of 92 infants (median age 4.2 months) who underwent TLA and dermatosurgery between 2005-2015.
- Postoperative data was available for 33 patients (35%).
Main Results:
- Common indications included melanocytic naevi (54) and haemangiomas (23).
- Lesions were primarily located on the scalp/neck (31) and extremities (31).
- No local anaesthesia side-effects were noted; minor complications included pain (3%), wound healing issues (3%), and scarring (6%).
Conclusions:
- TLA combined with dermatosurgery is a safe and effective outpatient option for infant skin lesions.
- The procedure offers excellent cosmetic results with minimal risks and the advantage of extended postoperative analgesia.
Background:
Early paediatric dermatosurgery reveals excellent cosmetic results due to high skin elasticity and pronounced capacity to recover from trauma. Furthermore, the size of skin lesions increases during life proportionally to skin growth and therefore early removal is of major importance. Selected local anaesthetics like prilocaine can cause methaemoglobinemia. However, in contrast to general anaesthesia, many other local anaesthetics do not bare any major risks for infants.
Objective:
In this retrospective study, we analysed infants aged less than 7 months receiving tumescent local anaesthesia (TLA) followed by dermatosurgery at our department between 2005 and 2015. The analysis is mainly based on our records. Additional information for a subset of patients was gained by a postoperative survey.
Methods:
Ninety-two infants (39 male, 53 female) with a median age of 4.2 months (range: 1.5 months; 6.7 months) were included in this study. Additional postoperative information was available for 33 of the 92 studied patients (35%).
Results:
Infants were mainly operated for removal of a melanocytic naevus (n = 54), followed by haemangioma (n = 23), naevus sebaceous (n = 6) and other lesions (n = 9). The lesions were located on the scalp or neck (n = 31), on the extremities (n = 31), on the trunk (n = 21), in the face (n = 6) or on the buttocks (n = 3). The median size of excision was 509 mm2 (range: 16 mm2 ; 3600 mm2 ). Primary defect closure was performed by intracutaneous (n = 68) or extracutaneous (n = 24) suture techniques. No side-effects of local anaesthesia were observed in any patient. Postoperative complications include pain (1/33; 3%), wound-healing disorder (1/33; 3%) and visible severe scarring (2/33; 6%).
Conclusions:
The combination of TLA and dermatosurgery in infants is a suitable outpatient treatment option for small lesions without any major risks or side-effects and the benefit of prolonged postoperative analgesia.
Related Concept Videos
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Chemistry and Structure-Activity Relationship

