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Updated: Feb 27, 2026
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Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis
Published on: October 2, 2020
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[Hemodialysis and cardiovascular outcome]
Laura Panicali1, Fabiana Brigante1, Elena Mancini1
1U.O. Nefrologia, Dialisi, Ipertensione Policlinico Universitario S.Orsola-Malpighi, Bologna, Italy.
Summary
Hemodialysis patients face high cardiovascular risks and mortality. New treatments like hemodiafiltration and tailored prescriptions can improve hemodynamic stability and patient outcomes.
Area of Science:
- Nephrology
- Cardiology
- Biomedical Engineering
Background:
- Hemodialysis (HD) patients have high mortality (15-20% yearly), primarily from cardiovascular events.
- Uremia and HD treatment itself introduce risks: inflammation, fluid overload, autonomic dysfunction, and hemodynamic instability.
- Intra-dialysis hypotension (IDH) is linked to organ hypoperfusion and poor long-term outcomes.
Purpose of the Study:
- To review risk factors for cardiovascular events in hemodialysis patients.
- To discuss technological advancements and alternative treatments improving hemodynamic tolerance.
- To emphasize personalized hemodialysis prescriptions for better cardiovascular outcomes.
Main Methods:
- Review of existing literature on hemodialysis complications and cardiovascular risks.
- Analysis of technological improvements in dialysis monitoring (e.g., blood volume, temperature).
- Evaluation of emerging treatments like hemodiafiltration (HDF) versus conventional HD.
Main Results:
- Advanced monitoring systems improve hemodynamic stability during HD.
- Hemodiafiltration may reduce IDH and cardiovascular mortality compared to conventional HD.
- Personalized HD prescriptions are crucial for managing hemodynamic tolerance.
Conclusions:
- Tailoring HD prescriptions and considering advanced treatments like HDF can mitigate risks.
- Focusing on hemodynamic stability is key to improving cardiovascular outcomes in HD patients.
- High-risk patients (diabetic, elderly, prior cardiovascular events) benefit most from optimized treatment strategies.
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