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Updated: Feb 27, 2026

Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography
Published on: June 21, 2024
[Imaging in CKD]
Carlo Ratti1, Laura Grassi2, Emiliana Ferramosca3
1Unità Operativa di Cardiologia, Ospedale Ramazzini, Carpi, Modena, Italy.
Insights
Imaging plays a vital role in assessing cardiovascular disease in chronic kidney disease (CKD) patients. Advanced imaging techniques are crucial for accurate risk stratification and managing myocardial and vascular complications in CKD.
Area of Science:
- Cardiology
- Nephrology
- Medical Imaging
Background:
- Cardiovascular disease (CVD) is a major cause of morbidity and mortality in patients with chronic kidney disease (CKD).
- CKD patients exhibit high prevalence of myocardial structural/functional alterations and severe vasculopathy.
- Accurate risk stratification is essential for managing CVD in CKD patients.
Purpose of the Study:
- To review the indications, strengths, and weaknesses of various imaging modalities for evaluating myocardial and vascular disease in CKD patients.
- To highlight the importance of sophisticated imaging for risk assessment in this high-risk population.
Main Methods:
- Review of invasive and non-invasive imaging techniques.
- Analysis of imaging's role in assessing atherosclerosis and arteriosclerosis in CKD.
- Exploration of imaging for evaluating myocardial and vascular pathology.
Main Results:
- Imaging demonstrates significant potential in reducing cardiovascular morbidity and mortality in the general population and CKD patients.
- CKD is associated with prevalent atherosclerosis and arteriosclerosis, necessitating advanced imaging.
- Sophisticated imaging is required for accurate risk assessment of cardiac and vascular disease in CKD.
Conclusions:
- Advanced imaging modalities are indispensable for comprehensive cardiovascular risk assessment in chronic kidney disease.
- Understanding the capabilities of various imaging techniques aids in optimizing patient management and outcomes.
- Further research into novel imaging applications can enhance the care of CKD patients with cardiovascular complications.
Abstract:
Imaging has contributed to the successful reduction of cardiovascular morbidity and mortality in the general population and it has demonstrated excellent potential among patients with chronic kidney disease (CKD). The well-known severity of cardiovascular disease in patients suffering from CKD requires an accurate risk stratification of these patients in several clinical situations. Alterations of both structure and function of the myocardium as well as severe vasculopathy are highly prevalent in patients with advanced CKD. Hence sophisticated imaging techniques are at times necessary to make an accurate assessment of risk. Two main forms of arterial pathology develop in patients with CKD: atherosclerosis, with accumulation of inflammatory cells, lipids, fibrous tissue and calcium in the sub-intimal space of the artery, and arteriosclerosis. The latter is characterized by thickening and calcification of the muscular layer of the arterial wall and it is not necessarily associated with typical atherosclerotic changes. This review explores the indications, strengths and weaknesses of several invasive and non-invasive imaging modalities employed to evaluate myocardial and vascular disease in CKD.
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