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Relationship between pharmacotherapy complexity and patient satisfaction with treatment for hepatitis C

Maria de Las Aguas Robustillo-Cortés1, Carmen Victoria Almeida-González2, Ramón Morillo-Verdugo3

  • 1Hospital Universitario de Valme. South Seville AGS (Healthcare Management Area).. aguasrobustillo@gmail.com.

Farmacia Hospitalaria : Organo Oficial De Expresion Cientifica De La Sociedad Espanola De Farmacia Hospitalaria
|July 8, 2017
PubMed

Insights

Treatment complexity for hepatitis C significantly impacts patient satisfaction and treatment outcomes. Simplifying medication regimens enhances patient satisfaction and improves the likelihood of achieving a sustained viral response.

Area of Science:

  • Hepatology and Gastroenterology
  • Pharmacoeconomics
  • Patient-Reported Outcomes

Background:

  • Hepatitis C virus (HCV) infection requires complex treatment regimens.
  • Patient satisfaction is a crucial factor in treatment adherence and success.
  • Understanding the link between treatment complexity and satisfaction is vital for optimizing care.

Purpose of the Study:

  • To investigate the relationship between the complexity of hepatitis C treatment and patient satisfaction.
  • To identify specific factors of treatment complexity that influence patient satisfaction.
  • To determine if treatment complexity affects the achievement of Sustained Viral Response (SVR).

Main Methods:

  • An observational, prospective, single-center study involving 171 HCV patients treated between October 2014 and February 2016.
  • Patient satisfaction was assessed using the HCV-ESTAR questionnaire (0-60 score), measuring clinical and lifestyle satisfaction.
  • Treatment complexity was quantified using the Medication Regimen Complexity Index (MRCI), analyzing prescribed medications and concomitant drug use.

Main Results:

  • The mean patient satisfaction score was 47.9±7.5, with high reliability for the questionnaire.
  • A significant correlation was found between treatment complexity and patient satisfaction (P<0.05).
  • Reductions in the Complexity Index and Concomitant Medication Index led to significant increases in satisfaction, and higher satisfaction correlated with a higher SVR rate (p=0.029).

Conclusions:

  • Increased pharmacotherapeutical complexity negatively impacts patient satisfaction in hepatitis C treatment.
  • Simplifying treatment regimens can enhance patient satisfaction.
  • Patient satisfaction, influenced by treatment complexity, is associated with improved outcomes, including higher rates of Sustained Viral Response.
Abstract

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