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Updated: Feb 27, 2026

Three-Dimensional Reconstruction of Orbital Fractures
Published on: May 16, 2025
Paediatric orbital cellulitis and the relationship to underlying sinonasal anatomy on computed tomography
R A Crosbie1, W A Clement1, H Kubba1
1Department of Paediatric Otorhinolaryngology,Royal Hospital for Children,Glasgow,Scotland,UK.
Insights
This study found no link between sinonasal anatomical variants, like septal deviation, and the risk of orbital cellulitis in children. These common nasal variations do not appear to predispose children to this serious eye infection or its complications.
Area of Science:
- Otolaryngology
- Pediatric Ophthalmology
- Medical Imaging
Background:
- Orbital cellulitis is a serious infection requiring prompt treatment.
- Sinonasal anatomical variants are common in children.
- The role of sinonasal variants in predisposing to orbital complications is unclear.
Purpose of the Study:
- To investigate the association between sinonasal anatomical variants and the risk of developing orbital cellulitis and its complications in children.
- To determine if specific variants like septal deviation or concha bullosa increase susceptibility.
Main Methods:
- Retrospective case-control series.
- Analysis of computed tomography (CT) scans in children with periorbital cellulitis who developed orbital cellulitis or abscesses.
- Evaluation of sinonasal anatomical variants: septal deviation and concha bullosa.
Main Results:
- Thirty children (mean age 7 years) with a Chandler score ≥2 were included.
- No association was found between concha bullosa and the side of disease (OR=1).
- No statistically significant difference in septal deviation and ipsilateral orbital infection (p=0.125).
Conclusions:
- No statistical correlation exists between sinonasal bony or cartilaginous anatomical variants and orbital complications of acute rhinosinusitis in the pediatric cohort.
- Findings do not support the theory that these variants predispose children to orbital cellulitis or its complications.
- Further research may be needed to explore other potential risk factors.
Objective:
To assess if there is an association between sinonasal anatomical variants and the risk of developing orbital cellulitis and associated complications, in children.
Methods:
A retrospective case-control series was conducted, examining computed tomography confirmed sinonasal anatomical variants of septal deviation and concha bullosa in children who presented with periorbital cellulitis who went on to develop orbital cellulitis and abscesses.
Results:
Thirty children had a Chandler score of 2 or greater on computed tomography. Mean age was seven years and there was relatively equal sex distribution. There was no association between presence of concha bullosa and side of disease (odds ratio = 1), and no statistically significant difference between septal deviation and ipsilateral orbital infection (p = 0.125).
Conclusion:
There was no statistical correlation between any sinonasal bony or cartilaginous anatomical variants on computed tomography and orbital complications of acute rhinosinusitis in our paediatric cohort. The findings do not support the theory that these anatomical variants predispose to orbital cellulitis occurring in these children, nor complications thereof.
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