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Related Experiment Video

Updated: Feb 27, 2026

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device

Published on: August 30, 2016

Mucosal Bioengineering: Gut in a Dish.

Ivaylo I Ivanov¹

¹Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

Trends in Immunology

|July 8, 2017

Summary

This summary is machine-generated.

Researchers developed a new organ culture system to study complex interactions between gut microbes and intestinal tissues. This novel approach improves the ability to dissect these crucial host-microbe relationships.

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Last Updated: Feb 27, 2026

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device

Published on: August 30, 2016

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Area of Science:

Microbiology
Gastroenterology
Host-Microbe Interactions

Background:

Studying the gut microbiome and its interaction with intestinal tissues is complex.
The inaccessibility of the intestinal environment poses challenges for research.

Purpose of the Study:

To introduce a novel organ culture system for studying host-microbe interactions.
To enhance the dissection of commensal microbe and host intestinal tissue networks.

Main Methods:

Development of a novel organ culture system.
Utilizing the system to observe microbial interactions with intestinal tissues.

Main Results:

The study reports a new organ culture system.
This system enhances the ability to study host-microbe interactions in the gut.

Conclusions:

The novel organ culture system provides a valuable tool for investigating host-microbe dynamics.
This advancement will facilitate a deeper understanding of intestinal tissue networks and commensal microbes.