A Multicomponent Approach to Evaluating a Pre-exposure Prophylaxis (PrEP) Implementation Program in Five Agencies in...

Area of Science:

• Public Health
• Infectious Disease Prevention
• Clinical Implementation Science

Background:

• Pre-exposure prophylaxis (PrEP) is a proven biomedical intervention for HIV prevention.
• Real-world implementation of PrEP faces challenges in clinical settings.
• Assessing PrEP's feasibility in diverse populations is crucial.

Purpose of the Study:

• To evaluate the implementation of PrEP in real-world clinical settings through the Targeted PrEP Implementation Program (TPIP).
• To assess provider capacity, participant adherence, and integration of PrEP into comprehensive care.
• To identify and address barriers to statewide PrEP delivery.

Main Methods:

• An 18-month project involving five statewide agencies.
• Targeted population: men who have sex with men at high risk for HIV.
• Data collection from multiple sources to assess implementation outcomes.

Main Results:

• 171 clients participated, with most successfully adhering to daily PrEP medication.
• Initial barriers were identified and addressed, facilitating routine delivery.
• PrEP was successfully integrated into comprehensive HIV prevention strategies.

Conclusions:

• Statewide implementation of PrEP is feasible in real-world clinical settings.
• Provider capacity building and resource development are key to successful PrEP programs.
• PrEP can be routinely delivered as part of integrated HIV prevention plans.