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Updated: Feb 27, 2026
Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
Published on: March 13, 2018
Complete Genome Sequences of 15 Chikungunya Virus Isolates from Puerto Rico
Wes A Sanders1,2, Kristin Long3, Brenda Rivera4
1Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
Abstract:
Here, we report the complete genome sequences of 15 chikungunya virus strains isolated from human plasma from infected patients in Puerto Rico. The results show that currently circulating chikungunya strains in Puerto Rico are closely related.
Insights
This study sequenced 15 chikungunya virus strains from Puerto Rico. The findings reveal that the currently circulating chikungunya virus strains in the region are genetically similar.
Area of Science:
- Virology
- Genomics
- Epidemiology
Background:
- Chikungunya virus (CHIKV) causes febrile illness with significant morbidity.
- Understanding the genetic diversity of circulating CHIKV strains is crucial for public health surveillance and control.
Purpose of the Study:
- To determine the genetic relatedness of chikungunya virus strains currently circulating in Puerto Rico.
- To provide genomic data for ongoing epidemiological investigations of CHIKV outbreaks.
Main Methods:
- Whole-genome sequencing of 15 chikungunya virus isolates from human plasma.
- Phylogenetic analysis to assess genetic relationships between viral strains.
Main Results:
- Complete genome sequences for 15 CHIKV strains were obtained.
- Phylogenetic analysis indicated that the circulating CHIKV strains in Puerto Rico are closely related.
- This suggests a recent common ancestor or limited introduction events.
Conclusions:
- The current chikungunya virus population in Puerto Rico exhibits low genetic diversity.
- These findings support ongoing surveillance efforts and inform public health strategies for CHIKV management in the region.
