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Ignorability for general longitudinal data
D M Farewell1, C Huang2, V Didelez3
1Division of Population Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4YS, U.K.
Likelihood factors that can be disregarded for causal inference, termed ignorable, are closely linked to identifying causal effects using covariate adjustment. A new graphical condition called stability, analogous to missingness at random, applies to longitudinal data even without missing values.
Area of Science:
- Causal inference
- Longitudinal data analysis
- Statistical modeling
Background:
- Identifying causal effects is crucial in many scientific fields.
- Covariate adjustment is a common method for causal inference.
- The concept of ignorability is key to valid causal effect estimation.
Purpose of the Study:
- To demonstrate the link between ignorability and causal effect identification via covariate adjustment.
- To introduce a graphical condition, stability, for assessing ignorability in longitudinal data.
- To provide a formulation of ignorability not reliant on missing data concepts.
Main Methods:
- Developing a graphical condition termed stability.
- Applying stability to general longitudinal data.
- Illustrating stability assessment with examples.
Main Results:
- Established a close relationship between ignorability and causal effect identification through covariate adjustment.
- Introduced stability as a graphical condition analogous to missingness at random for longitudinal data.
- Showcased the applicability of stability in scenarios without actual missing data.
Conclusions:
- Ignorability and causal effect identification are tightly linked, particularly with covariate adjustment.
- Stability offers a robust graphical criterion for ignorability in longitudinal studies, irrespective of missing data.
- The stability condition provides a practical tool for assessing assumptions in causal inference for longitudinal data.
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