Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Waves01:23

Brain Waves

4.4K
Brain waves are electrical signals generated by the neurons in the brain, which are regularly monitored to measure mental activities. Brain waves and their frequency ranges can be measured using an electroencephalogram or EEG. There are four main types of brain waves, each with distinct characteristics:
4.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preconception counselling components in women with serious mental illness: a scoping review.

Journal of reproductive and infant psychology·2026
Same author

Lorazepam during breastfeeding: a pharmacokinetic case report and exploratory pharmacovigilance assessment - a contribution from the ConcePTION project.

Frontiers in pharmacology·2026
Same author

Time-dependent pattern of liver injury biomarkers in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia.

European journal of pediatrics·2026
Same author

Assessing peripheral oxytocin and cortisol levels and epigenetic variations of oxytocin receptor and glucocorticoid receptor genes in school-aged preterm-born children.

Progress in neurobiology·2026
Same author

Correction: Retrieving interpretability to support vector machine regression models in dynamic system identification.

Frontiers in artificial intelligence·2026
Same author

Neonatal PBPK model of midazolam and its metabolites for perinatal asphyxia and therapeutic hypothermia.

British journal of clinical pharmacology·2026

Related Experiment Video

Updated: Feb 27, 2026

Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates
05:58

Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates

Published on: September 6, 2017

40.8K

Relation Between EEG Activity and Brain Oxygenation in Preterm Neonates.

Alexander Caicedo1,2, Liesbeth Thewissen3, Anne Smits3,4

  • 1Department of Electrical Engineering, STADIUS-ESAT, KU Leuven, Leuven, Belgium. acaicedo@esat.kuleuven.be.

Advances in Experimental Medicine and Biology
|July 8, 2017
PubMed
Summary

This study links brain oxygenation (FTOE) to brain activity (EEG amplitude) in sedated neonates. Higher fractional tissue oxygen extraction correlated with increased EEG amplitude, aiding in monitoring neonatal brain function.

Keywords:
EEGFlow-metabolic couplingNIRSPropofol

More Related Videos

Preterm EEG: A Multimodal Neurophysiological Protocol
19:32

Preterm EEG: A Multimodal Neurophysiological Protocol

Published on: February 18, 2012

29.1K
How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children
07:27

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children

Published on: August 19, 2020

12.7K

Related Experiment Videos

Last Updated: Feb 27, 2026

Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates
05:58

Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates

Published on: September 6, 2017

40.8K
Preterm EEG: A Multimodal Neurophysiological Protocol
19:32

Preterm EEG: A Multimodal Neurophysiological Protocol

Published on: February 18, 2012

29.1K
How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children
07:27

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children

Published on: August 19, 2020

12.7K

Area of Science:

  • Neuroscience
  • Medical Engineering
  • Neonatal Care

Background:

  • Neonatal brain function monitoring is crucial.
  • Near-infrared spectroscopy (NIRS) and electroencephalography (EEG) are non-invasive tools.
  • Understanding the relationship between brain oxygenation and electrical activity is key.

Purpose of the Study:

  • To investigate the correlation between brain oxygenation parameters and EEG features in sedated neonates.
  • To assess if NIRS-derived measures can predict EEG-based functional indicators.
  • To explore novel methods for monitoring neonatal brain health.

Main Methods:

  • Utilized NIRS to measure regional cerebral oxygen saturation (rScO2) and calculate fractional tissue oxygen extraction (FTOE).
  • Analyzed EEG signals for features like inter-burst interval (IBI) duration/amplitude and overall EEG amplitude.
  • Performed regression analysis to correlate NIRS-derived values with EEG features in 22 sedated neonates.

Main Results:

  • A significant positive correlation was found between higher FTOE values and increased EEG amplitude.
  • This suggests a link between oxygen extraction and the intensity of brain electrical activity.
  • Specific EEG features like IBI were also analyzed in relation to oxygenation.

Conclusions:

  • Higher fractional tissue oxygen extraction is associated with greater EEG amplitude in sedated neonates.
  • These findings suggest potential for combined NIRS-EEG monitoring in neonatal intensive care.
  • This approach may enhance the assessment of adequate brain function and oxygenation in vulnerable infants.