Primary diffuse large B-cell lymphoma of the frontal sinus

Area of Science:

• Oncology
• Otorhinolaryngology
• Pathology

Background:

• Primary frontal sinus lymphoma is an exceptionally rare malignancy.
• Symptoms are often misleading due to tumor mass effect, delaying diagnosis.

Observation:

• A 43-year-old male presented with a 4-week history of painful swelling over the right frontal sinus.
• The swelling was gradually enlarging and diffuse in nature.

Findings:

• The case highlights diffuse large B-cell lymphoma presenting as a primary frontal sinus tumor.
• Diagnostic challenges include the rarity of the condition and nonspecific initial symptoms.

Implications:

• Emphasizes the critical need for early recognition and diagnosis of primary frontal sinus lymphoma.
• This case contributes to understanding the clinical presentation and management of this rare entity.