Related Experiment Video
Updated: Feb 27, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Associations between birthweight and overweight and obesity in school-age children
N Kapral1, S E Miller1, R J Scharf1
1Department of Pediatrics, University of Virginia, Charlottesville, VA, USA.
Insights
High birthweight in term and preterm infants is linked to increased obesity risk in school-aged children. Early counseling for families with large infants may help prevent future obesity.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- The relationship between birthweight and subsequent obesity risk is not fully understood.
- Childhood obesity is a significant public health concern with long-term implications.
Purpose of the Study:
- To investigate the association between birthweight and obesity risk in a nationally representative cohort of children.
- To examine changes in Body Mass Index (BMI) z-score from kindergarten to second grade in relation to birthweight.
Main Methods:
- Utilized linear and logistic regression analyses on data from the Early Childhood Longitudinal Study-Kindergarten Cohort 2011.
- Included 10,186 term and preterm children, adjusting for covariates like sex, race/ethnicity, parental education, and household income.
- Assessed relationships between birthweight categories (normal, high, large-for-gestational-age, small-for-gestational-age) and obesity status and BMI z-score changes.
Main Results:
- High birthweight (HBW) term infants and large-for-gestational-age (LGA) preterm infants showed significantly higher BMI z-scores.
- HBW term infants had increased odds of obesity by kindergarten (aOR 1.91).
- LGA preterm infants had higher obesity odds in first grade (aOR 2.34), while small-for-gestational-age preterm infants showed higher odds in second grade (aOR 2.26).
Conclusions:
- High birthweight in term infants and LGA in preterm infants are associated with increased odds of school-age obesity.
- These findings suggest that birthweight is a critical factor in predicting future obesity.
- Healthcare providers should consider counseling families of infants with high birthweight to mitigate future obesity risks.
Background:
Relationships between birthweight and future obesity risk remain unclear.
Objective:
To assess associations between birthweight and later obesity in a nationally representative cohort of early school-aged children.
Methods:
We used linear and logistic regression to evaluate 10 186 term- or preterm children in the Early Childhood Longitudinal Study-Kindergarten Cohort 2011 for relationships between birthweight and later obesity and change in BMI z-score from kindergarten-to-second grade. All analyses were adjusted for sex, race/ethnicity, parental education and household income.
Results:
Compared to children born normal birthweight (NBW), high birthweight (HBW) term children and large-for-gestational-age (LGA) preterm children had significantly greater BMI z-scores from kindergarten-to-second grade (p < 0.001). Term children born HBW had higher odds of obesity by kindergarten (adjusted odds ratios [aOR] 1.91, p < 0.0001). Among preterm children, odds of obesity was higher among LGA children starting in first grade (aOR 2.34, p < 0.05) and among small-for-gestational age children in second grade (aOR 2.26, p < 0.05). Compared to NBW children, HBW children had greater change in BMI z-score between kindergarten-first grade (p < 0.01).
Conclusions:
High birthweight term and LGA preterm children had increased adjusted odds of obesity in school-age compared to their NBW counterparts. Physicians may provide counselling early in life for families of large infants to help prevent future obesity.
Related Concept Videos
Obesity
Drug Dosing: Obese Patients
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Bullying
Nature and Nurture

