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Updated: Feb 27, 2026
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Published on: March 30, 2015
Differentiation of low- and high-grade clear cell renal cell carcinoma: Tumor size versus CT perfusion parameters
Chao Chen1, Qinqin Kang2, Bing Xu2
1Department of Radiology, PLA Army General Hospital, Beijing 100700, China.
Purpose:
To compare the utility of tumor size and CT perfusion parameters for differentiation of low- and high-grade clear cell renal cell carcinoma (RCC).
Materials And Methods:
Tumor size, Equivalent blood volume (Equiv BV), permeability surface-area product (PS), blood flow (BF), and Fuhrman pathological grading of clear cell RCC were retrospectively analyzed.
Results:
High-grade clear cell RCC had significantly higher tumor size and lower PS than low grade. Tumor size positively correlated with Fuhrman grade, but PS negatively did.
Conclusions:
Tumor size and PS were significantly independent indexes for differentiating high-grade from low-grade clear cell RCC.
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