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Computer-aided detection and quantification of endolymphatic hydrops within the mouse cochlea in vivo using optical
George S Liu1, Jinkyung Kim1, Brian E Applegate2
1Stanford University, Department of Otolaryngology-Head and Neck Surgery, Stanford, California, United States.
Journal of Biomedical Optics
|July 9, 2017
Abstract:
Diseases that cause hearing loss and/or vertigo in humans such as Meniere’s disease are often studied using animal models. The volume of endolymph within the inner ear varies with these diseases. Here, we used a mouse model of increased endolymph volume, endolymphatic hydrops, to develop a computer-aided objective approach to measure endolymph volume from images collected
