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Published on: January 22, 2013
Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography
Hsiang-Chieh Lee1, Osman O Ahsen1, Jonathan J Liu1
1Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Cambridge, Massachusetts, United States.
Abstract:
Radiofrequency ablation (RFA) is widely used for the eradication of dysplasia and the treatment of early stage esophageal carcinoma in patients with Barrett’s esophagus (BE). However, there are several factors, such as variation of BE epithelium (EP) thickness among individual patients and varying RFA catheter-tissue contact, which may compromise RFA efficacy. We used a high-speed optical coherence tomography (OCT) system to identify and monitor changes in the esophageal tissue architecture from RFA. Two different OCT imaging/RFA application protocols were performed using an
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