Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Convolutional Graph Isomorphism Network to Detect Glaucomatous Visual Field Defects.

Ophthalmology science·2026
Same author

Editorial: Imaging in glaucoma.

Frontiers in medicine·2026
Same author

Influence of Intraocular Pressure on Clinical Decision-Making in Glaucoma Management.

JAMA ophthalmology·2026
Same author

Performance of a Small Language Model Versus a Large Language Model in Answering Glaucoma Frequently Asked Patient Questions: Development and Usability Study.

JMIR AI·2026
Same author

Artificial Intelligence-Guided Endpoint Selection for Neuroprotection Trials in Glaucoma.

American journal of ophthalmology·2026
Same author

Time to Identify Glaucoma Progression Given Typical Visual Field Testing Frequencies in a US Nationwide Insured Population.

Ophthalmology. Glaucoma·2025
Same journal

Impact of Subretinal Drusenoid Deposits on Ellipsoid Zone-Related Thickness Metrics.

Investigative ophthalmology & visual science·2026
Same journal

Proteomic Profiling of Optic Nerves From SMOX-Deficient Mice Identifies Regulators of Neuroinflammation and Axonal Damage in Optic Neuritis.

Investigative ophthalmology & visual science·2026
Same journal

Aflibercept and Faricimab Equipotently Restore Endothelial Barrier Function.

Investigative ophthalmology & visual science·2026
Same journal

Spatial Decomposition of Longitudinal RNFL Maps Reveals Distinct Modes of Glaucomatous Progression With Structure-Function and Genetic Signatures.

Investigative ophthalmology & visual science·2026
Same journal

The CXXC1-IGFBP6 Axis Maintains Corneal Epithelial Differentiation via H3K4me3-Dependent Transcriptional Activation.

Investigative ophthalmology & visual science·2026
Same journal

Archetypal Visual Field Analysis of Patients With Chronic Leber Hereditary Optic Neuropathy in Relation to Visual Recovery.

Investigative ophthalmology & visual science·2026
See all related articles

Related Experiment Video

Updated: Feb 27, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

2.0K

Wayfinding and Glaucoma: A Virtual Reality Experiment.

Fábio B Daga1, Eduardo Macagno2, Cory Stevenson2

  • 1Visual Performance Laboratory, University of California San Diego, La Jolla, California, United States.

Investigative Ophthalmology & Visual Science
|July 9, 2017
PubMed
Summary
This summary is machine-generated.

Glaucoma patients struggle with complex virtual reality navigation tasks, indicating visual field loss impairs spatial mapping. This research highlights virtual reality

More Related Videos

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.9K
Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

993

Related Experiment Videos

Last Updated: Feb 27, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

2.0K
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.9K
Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

993

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Cognitive Psychology

Background:

  • Wayfinding is essential for daily activities.
  • Glaucoma is a progressive optic neuropathy leading to visual field loss.
  • Impaired spatial cognition can result from visual field deficits.

Purpose of the Study:

  • To investigate the impact of glaucomatous visual field loss on wayfinding behavior.
  • To assess wayfinding performance in an immersive virtual reality (VR) environment.
  • To differentiate between allocentric and egocentric spatial representations in glaucoma patients.

Main Methods:

  • A cross-sectional study involving 31 glaucoma patients and 20 healthy controls.
  • Wayfinding tasks were conducted in a VR environment, modeled after the Morris water maze.
  • Two rooms were used: Room A (complex visual cues for allocentric mapping) and Room B (single cue for egocentric mapping).

Main Results:

  • Glaucoma patients took significantly longer (35.0s vs 24.4s) in Room A (allocentric task) (P=0.001).
  • No significant difference in task completion time was observed in Room B (egocentric task) (26.2s vs 23.4s, P=0.514).
  • Worse binocular mean sensitivity in glaucoma patients correlated with increased wayfinding time in Room A (3.4% per 1-dB loss, P=0.001).

Conclusions:

  • Glaucoma patients exhibit impaired allocentric wayfinding in VR, suggesting visual field loss affects spatial cognitive map construction.
  • Virtual reality offers a valuable tool for assessing functional vision in clinical trials.
  • Findings underscore the link between visual field deficits and spatial navigation challenges.